Sharon L Reed Selected Research

Auranofin (Ridaura)

1/2017	Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent.
5/2016	X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
1/2015	New drug target in protozoan parasites: the role of thioredoxin reductase.
1/2014	Auranofin is highly efficacious against Toxoplasma gondii in vitro and in an in vivo experimental model of acute toxoplasmosis.
5/2013	A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia.
1/2013	Reprofiled drug targets ancient protozoans: drug discovery for parasitic diarrheal diseases.
6/2012	A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sharon L Reed Research Topics

Disease

8	Infections 03/2022 - 05/2004
6	Amebiasis (Amoebiasis) 05/2016 - 01/2002
4	Rheumatoid Arthritis 01/2017 - 06/2012
3	Toxoplasmosis 01/2018 - 05/2004
2	Invasive Pulmonary Aspergillosis 03/2019 - 01/2019
2	Amebic Dysentery (Amoebic Dysentery) 06/2012 - 01/2012
1	COVID-19 01/2020
1	Giardiasis 09/2019
1	Aspergillosis 03/2019
1	Hematologic Neoplasms (Hematological Malignancy) 01/2019
1	Protozoan Infections 01/2018
1	Bacterial Infections (Bacterial Infection) 10/2017
1	Pancreatitis 10/2017
1	Pancreatic Pseudocyst 10/2017
1	Parasitic Diseases (Parasitic Disease) 01/2017
1	Body Weight (Weight, Body) 01/2014
1	Diarrhea 01/2013
1	Cysts 01/2013
1	Neglected Diseases 01/2013
1	Amebic Liver Abscess 06/2012
1	Muscle Cramp (Cramp) 01/2012
1	Tuberculosis (Tuberculoses) 09/2011
1	Inflammation (Inflammations) 06/2010
1	Encephalitis (Encephalitis, Rasmussen) 04/2009
1	Strongyloidiasis 03/2009
1	Coinfection 03/2009
1	Meningitis 01/2007

Drug/Important Bio-Agent (IBA)

7	Auranofin (Ridaura)FDA Link 01/2017 - 06/2012
5	Cysteine Proteases (Cysteine Protease)IBA 03/2012 - 01/2002
4	GoldIBA 01/2017 - 01/2014
3	divinyl sulfoneIBA 01/2018 - 06/2010
3	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 07/2007
3	Pharmaceutical PreparationsIBA 05/2016 - 06/2012
2	galactomannanIBA 03/2019 - 01/2019
2	CathepsinsIBA 01/2018 - 05/2004
1	beta Lactam AntibioticsIBA 03/2022
1	beta-Lactamases (beta-Lactamase)IBA 03/2022
1	Immunoglobulin M (IgM)IBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	A 7 (A-7)IBA 09/2019
1	Metronidazole (Metric)FDA LinkGeneric 09/2019
1	N- pip- phenylalanine- homophenylalanine- vinyl sulfone phenylIBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2017
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2014
1	Antiparasitic Agents (Antiparasitics)IBA 01/2013
1	OligosaccharidesIBA 11/2012
1	Galactose (Galactopyranose)FDA LinkGeneric 11/2012
1	Virulence Factors (Pathogenicity Factors)IBA 11/2012
1	SugarsIBA 11/2012
1	LectinsIBA 11/2012
1	GalactosamineIBA 11/2012
1	CathelicidinsIBA 01/2012
1	Antimicrobial PeptidesIBA 01/2012
1	EnzymesIBA 06/2010
1	Interleukin-6 (Interleukin 6)IBA 04/2009
1	CytokinesIBA 04/2009
1	Interleukin-8 (Interleukin 8)IBA 04/2009
1	Ivermectin (Mectizan)FDA Link 03/2009
1	Cathepsin CIBA 02/2007
1	DNA (Deoxyribonucleic Acid)IBA 01/2007
1	Cathepsin BIBA 05/2004

Therapy/Procedure

5	Therapeutics 09/2019 - 06/2012
1	Lenses 09/2011